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Ibuprofen good for high altitude flying?

In the UK, it can be bought from supermarket shelves as 200mg and over the counter (ie without prescription) as 400mg from pharmacies.

Apparently, and I have yet to have this confirmed by a doctor or pharmacist, if you take two 200mg tablets it’s pretty much the same as taking one 400mg. But no-one has told the Government, and they are too busy tearing themselves to pieces to work it out for themselves.

EGKB Biggin Hill

If you believed that, you’d believe that homeopathy doesn’t work. The idea that larger doses of a drug could be more efficacious than smaller is ridiculous.

It’s clear that the best dose is .0000001mg taken once a month. That should be good for allowing you to 41,000’ without oxygen.

EGKB Biggin Hill

Think the aircraft might need some of those tablets as well to gt to FL410.

If you want to get it up, that’s a completely different tablet, now also available without prescription.

Last Edited by Timothy at 17 Jun 08:38
EGKB Biggin Hill

Timothy wrote:

If you believed that, you’d believe that homeopathy doesn’t work. The idea that larger doses of a drug could be more efficacious than smaller is ridiculous.

I’m not at all saying the article is correct, but the rate of which the active substance is released can clearly be different if you take two x mg tablets compared to one 2x mg tablet and that could make a difference in effect.

ESKC (Uppsala/Sundbro), Sweden

Airborne_Again wrote:

I’m not at all saying the article is correct, but the rate of which the active substance is released can clearly be different if you take two x mg tablets compared to one 2x mg tablet and that could make a difference in effect.

I think Timothy will need to be carful what he takes then and in what combination.

You might run into problems going to high without the corrct equipment.

So, if you can go to 180 on 400mg in one dose, can you get to 360 on two 200mg doses?

We must be told.

EGKB Biggin Hill

I thought the original post was a windup

Administrator
Shoreham EGKA, United Kingdom

Fuji_Abound wrote:

Oh no, you might think that, but one 400 is better than 2 200s.

https://www.empr.com/home/mpr-first-report/painweek-2012/painweek-2012-chronic-pain/single-400mg-dose-otc-ibuprofen-superior-to-200mg-for-pain-relief/

My understanding of that link is that they compared 400mg vs 200mg vs placebo. Not 400mg in one tablet vs in two tablets. I hear that the placebo effect actually makes it so that two tablets of 200mg are more efficient than one of 400mg.

Timothy wrote:

Apparently, and I have yet to have this confirmed by a doctor or pharmacist, if you take two 200mg tablets it’s pretty much the same as taking one 400mg. But no-one has told the Government, and they are too busy tearing themselves to pieces to work it out for themselves.

And you can overdose on taking the whole bottle, or several packs, of pills that you can buy at the supermarket. And also on the chemicals they sell.

Seriously, the way I see many people self-medicate, these kind of limitations make sense. Some have a system of “normal pain take one pill, big pain take two pills”. Some always take two pills, because they want an “effective dose”. Whether the pills contain 500mg of paracetamol or 1g doesn’t make a difference. It is by the number of pills. I kid you not. These are people that can count. Accountants, bank clerks, stuff like that. It never ceases to amaze me.

Some look at me with alarm when I take three pills of 200mg ibuprofen when the doctor wrote me a prescription of 1 pill of 600mg. Or when I swallow five pills of cardiac-dose aspirin (that’s 100mg).

Last Edited by lionel at 17 Jun 20:09
ELLX
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